Immunobiology : the immune system in health and disease /
Charles A. Janeway, Jr. .. [et al.].
- 6th ed.
- New York : Garland Science, c2005.
- xxiii, 823 p. : ill. (chiefly col.) ; 28 cm. + 1 CD-ROM (4 3/4 in.)
Includes bibliographical references and index.
Pt. 1. An introduction to immunobiology and innate immunity. Basic concepts in immunology -- Innate immunity -- Pt. 2. The recognition of antigen. Antigen recognition by B-cell and T-cell receptors -- The generation of lymphocyte antigen receptors -- Antigen presentation to T lymphocytes -- Pt. 3. The development of mature lymphocyte receptor repertoires. Signaling through immune system receptors -- The development and survival of lymphocytes -- Pt. 4. The adaptive immune response. T cell-mediated immunity -- The humoral immune response -- Adaptive immunity to infection -- Pt. 5. The immune system in health and disease. Failures of host defense mechanisms -- Allergy and hypersensitivity -- Autoimmunity and transplantation -- Manipulation of the immune response -- Pt. 6. The origins of immune responses. Evolution of the innate immune system.