000 04440cam a2200337 i 4500
001 29177
003 OSt
005 20250506092726.0
008 190702s2019 enka b 001 0 eng c
020 _a9780128168431
_q(pbk.)
040 _aNLM
_beng
_cNLM
_erda
082 7 4 _223
_a576.5
_bN976
245 1 0 _aNutritional epigenomics /
_cedited by Bradley S. Ferguson.
264 1 _aLondon, United Kingdom :
_bElsevier/Academic Press,
_c[2019]
300 _axxiii, 454 pages :
_billustrations ;
_c24 cm.
336 _atext
_btxt
_2rdacontent
337 _aunmediated
_bn
_2rdamedia
338 _avolume
_bnc
_2rdacarrier
490 1 _aTranslational epigenetics ;
_vvolume 14
504 _aIncludes bibliographical references and index.
505 0 _aSECTION I Introduction -- 1. Introduction to nutritional epigenomics -- SECTION II Epigenetic regulators -- 2. DNA methylation and chromatin modifications -- 3. Small non-coding RNAs as epigenetic regulators -- SECTION III Epigenomic regulation of disease -- 4. The impact of race and ethnicity in the social epigenomic regulation of disease -- 5. The epigenomic impact of methylation in metabolic dysfunction and cancer -- 6. The role for DNA/RNA methylation on neurocognitive dysfunctions -- 7. Histone acylation in the epigenomic regulation of insulin action and metabolic disease -- 8. Cancer and non-coding RNAs -- 9. Race in the social-epigenomic regulation of pre- and perinatal development -- 10. Maternal nutrition, epigenetic programming and metabolic syndrome -- 11. Epigenetic inheritance of metabolic signals -- 12. The paternal diet regulates the offspring epigenome and health -- SECTION V Nutritional epigenomics and the circadian clock -- 13. The interplay between diet, epigenetics and the circadian clock -- 14. Epigenetic regulation of the fetal circadian clock: implications for nutritional programming of circadian and metabolic function -- 15. The role for the microbiome in the regulation of the circadian clock and metabolism -- SECTION VI Carloric restriction and exercise in the epigenomic regulation of aging and disease -- 16. Epigenomic reprogramming of caloric restriction on aging -- 17. Dietary restriction in the epigenomic regulation of cardiovascular diseases -- 18. Epigenomic adaptations of exercise in the control of metabolic disease and cancer -- SECTION VII Macro- and micronutrients as epigenomic regulators of health and disease -- 19. B-vitamins and one-carbon metabolism: impacts on the epigenome during development -- 20. Food bioactives in the epigenomic regulation of metabolic disease -- 21. Stilbenoids as dietary regulators of the cancer epigenome -- 22. Regulation of non-coding RNAs by phytochemicals for cancer therapy -- 23. Short chain fatty acids as epigenetic and metabolic regulators of neurocognitive health and disease -- SECTION VIII Diet, epigenetics and the microbiome -- 24. Diet-microbiome interactions and the regulation of the epigenome -- 25. Gut dysbiosis and its epigenomic impact on disease -- 26. Microbiota, the brain and epigenetics
520 _a"Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition's role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet's role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders."--Provided by publisher.
650 4 _aNutrition
_xGenetic aspects.
650 4 _aEpigenetics.
700 1 _aFerguson, Bradley S.,
_eeditor.
776 0 8 _iElectronic version:
_tNutritional epigenomics.
_dLondon, United Kingdom : Academic Press, an imprint of Elsevier, 2019
_z9780128173107
_w(OCoLC)1110183967
830 0 _aTranslational epigenetics series ;
_vv. 14.
910 _aASEEL
942 _2ddc
_n0
_cBK
999 _c29177
_d29177